Learning Objectives

  • 1. Review the foundational role of the endothelium through a systems biology lens

  • 2. List the multiple roles of the endothelial glycocalyx (EGX), including its protective, regulatory, and communication roles for endothelial function

  • 3. Connect the role of sex hormones in cardiovascular outcomes

  • 4. Identify patients where EGX support would benefit hormone replacement therapy and/or overall health

  • 5. Utilize strategies to prevent vascular disease in those at risk and in those with subclinical vascular disease

About This Course

This course introduces and explains the role of the endothelial glycocalyx (EGX), the microscopically thin lining of every artery, vein, and capillary in the human body. 

Recent science has established that the EGX is a selectively permeable barrier that both protects and mediates essential endothelial functions. Almost every therapeutic intervention relies upon a healthy vascular system, including hormone replacement therapies.

Featuring family practitioner Kristine Burke, MD, IFMCP.

Accreditation Statements

In support of improving patient care, this activity has been planned and implemented by The Foundation of Care Management (FCM) and the Hormone Health Institute. FCM is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

  • Nursing

    This program is approved for 1 Nursing contact hour

  • Physicians

    This program is approved for 1 AMA Category 1 Credits TM

  • Pharmacists

    This program is approved for 1 Contact Hour Pharmacy Credit JA0007163-9999-22-011-H01-P

Disclosure Statements


Speaker Faculty:

Kristine Burke, MD Independent contractor relationship with Calroy Health Sciences; Independent contractor relationship with AND Health.


Planning Committee:

Angela DeRosa, DO Consultant relationship with Belmar Pharma; Ownership Interest relationship with Hormonal Health Institute.


Program Reviewers

Mary Corry, MSN and Dana Burnett, M. Ed. have no relevant financial relationships with ineligible companies to disclose.


All relevant financial relationships for faculty, planning committee and program reviewers have been reviewed and mitigated.

Course curriculum

  • 1


    • Overview: The New Key to Vascular Health: The Endothelial Glycocalyx

    • Accreditations & CMEs

    • Video: The New Key to Vascular Health: The Endothelial Glycocalyx ( 30-minute video)

    • Reference Material: Endothelium as an endocrine organ

    • CME Accreditation Examination & Instructions for Claiming CME Credits


Guest Instructor

Kristine Burke, MD

Dr. Burke, medical director and CEO of the True Health Center for Functional Medicine in El Dorado Hills, CA, specializes in family, sports, and functional medicine. She also has served as chief of family medicine at Mercy Hospital of Folsom, assistant clinical professor of preventive medicine at Loma Linda School of Medicine, and as an educator and facilitator for the Institute for Functional Medicine. Additionally, she contributed to the development of the COVID-19 Virtual Care pathway for VirtualPractices.org and The Institute for Functional Medicine’s COVID-19 Task Force. Dr. Burke received her M.D. at University of California School of Medicine in Davis, Calif., and is board certified in family medicine, sports medicine, and integrative medicine.